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Index > Protein center > SRD5A1(Gene name) > Human
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  • SRD5A1 (Gene name),
  • 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Protein name ),  S5A1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SRD5A1;
    Protein name:
    3-oxo-5-alpha-steroid 4-dehydrogenase 1;
    Alternative:
    Steroid 5-alpha-reductase 1(S5AR 1);SR type 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
    Subcellular Location:
    Microsome membrane Multi-pass membrane protein Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    259
    Sequence:
    50:
    MATATGVAEE | RLLAALAYLQ | CAVGCAVFAR | NRQTNSVYGR | HALPSHRLRV | 
    100:
    PARAAWVVQE | LPSLALPLYQ | YASESAPRLR | SAPNCILLAM | FLVHYGHRCL | 
    150:
    IYPFLMRGGK | PMPLLACTMA | IMFCTCNGYL | QSRYLSHCAV | YADDWVTDPR | 
    200:
    FLIGFGLWLT | GMLINIHSDH | ILRNLRKPGD | TGYKIPRGGL | FEYVTAANYF | 
    250:
    GEIMEWCGYA | LASWSVQGAA | FAFFTFCFLS | GRAKEHHEWY | LRKFEEYPKF | 
    259:
    RKIIIPFLF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    MIM:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Cat.:
    E1531h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Cat.:
    E1531m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Cat.:
    E1531b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Cat.:
    E1531r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Cat.:
    U1531r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Cat.:
    U1531h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Cat.:
    U1531b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Cat.:
    U1531m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Cat.:
    P1531Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Cat.:
    P1531Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Cat.:
    P1531Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Monoclonal Antibody for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Monoclonal Antibody for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Monoclonal Antibody for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Monoclonal Antibody for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Protein for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Protein for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Protein for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1
    Protein for Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1

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    Precision
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    Linearity
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    References
    1. 1.
      "Structural and biochemical properties of cloned and expressed human and rat steroid 5 alpha-reductases."
      Andersson S. , Russell D.W.
      Proc. Natl. Acad. Sci. U.S.A.87:3640-3644(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Characterization and chromosomal mapping of a human steroid 5 alpha-reductase gene and pseudogene and mapping of the mouse homologue."
      Jenkins E.P. , Hsieh C.L. , Milatovich A. , Normington K. , Berman D.M. , Francke U. , Russell D.W.
      Genomics11:1102-1112(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      Yu W. , Sarginson J. , Gibbs R.A.
      Submitted (1998-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Adrenal gland.
    5. 5.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    6. 6.
      NIEHS SNPs program
      Submitted (2003-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    7. 7.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Hippocampus.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Eye.
      tissue: Urinary bladder.
    10. 10.
      "New steroid 5alpha-reductase type I (SRD5A1) homologous sequences on human chromosomes 6 and 8."
      Eminovic I. , Liovic M. , Prezelj J. , Kocijancic A. , Rozman D. , Komel R.
      Pflugers Arch.442:R187-R189(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-98 AND 155-187
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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